Name: Florinef Tab 0.1mg Price in Pakistan
SKU: Eazy-medz 64251
Availability: InStock

Description

Florinef contains fludrocortisone acetate, a synthetic corticosteroid with potent mineralocorticoid properties. It is primarily used to replace endogenous hormones in conditions where the body does not produce sufficient steroids.

Mechanism of Action: Fludrocortisone acts on the distal renal tubules to enhance sodium reabsorption, increase potassium excretion, and elevate blood pressure. It helps maintain electrolyte balance and blood pressure in patients with adrenal insufficiency.

Dosage and Administration:

Addison’s Disease: The typical dosage ranges from 0.1 mg to 0.2 mg daily, based on individual patient needs and response.
Salt-Losing Adrenogenital Syndrome: Dosage is individualized; close monitoring of electrolyte levels and blood pressure is essential.
Administration: Florinef tablets are taken orally, preferably in the morning to align with the body’s natural cortisol rhythm.

Contraindications:

Systemic fungal infections.
Known hypersensitivity to fludrocortisone acetate or any component of the formulation.

Warnings and Precautions:

Infection Risk: Corticosteroids can mask signs of infection and may increase susceptibility.
Blood Pressure Monitoring: Regular monitoring is essential due to the risk of hypertension.
Electrolyte Imbalance: Monitor serum electrolytes regularly; watch for hypokalemia.
Bone Health: Long-term use may lead to osteoporosis; consider bone density monitoring.

Adverse Reactions:

Common: Hypertension, edema, hypokalemia.
Less Common: Muscle weakness, headache, gastrointestinal discomfort.
Rare but Serious: Congestive heart failure, peptic ulcers, pancreatitis.

Drug Interactions:

Diuretics: Increased risk of hypokalemia.
Anticoagulants: May alter the effects of warfarin.
Vaccines: Reduced efficacy of live vaccines; avoid concurrent use.

Use in Specific Populations:

Pregnancy: Use only if clearly needed; potential risks should be discussed with a healthcare provider.
Lactation: Caution is advised; it’s unknown if fludrocortisone is excreted in human milk.
Pediatrics: Use with caution; monitor growth and development.
Geriatrics: Increased risk of hypertension and osteoporosis; use the lowest effective dose.

Storage: